Bipolar disorder is generally characterized by unusual shifts in mood, energy, and activity levels. There are treatments for bipolar disorder and people with this condition can lead full, engaged and productive lives.

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Recognizing Bipolar Disorder: Manic & Depressive Episodes

People with bipolar disorder experience unusually intense emotional states called mood episodes. These differ from everyday emotional shifts in both their intensity and duration, and they can significantly impair functioning at home, work, or school.

Manic Episodes

  • Unusually elevated, expansive, or irritable mood
  • Markedly increased energy and activity
  • Dramatically decreased need for sleep
  • Racing thoughts and rapid, pressured speech
  • Impulsive or reckless decision-making
  • Inflated self-esteem or grandiosity

Depressive Episodes

  • Persistent sadness, emptiness, or hopelessness
  • Loss of interest in previously enjoyed activities
  • Fatigue, slowed thinking, and low motivation
  • Changes in sleep (insomnia or hypersomnia)
  • Difficulty concentrating or making decisions
  • Feelings of worthlessness or excessive guilt

Types of Bipolar Disorder

Bipolar disorder is not one-size-fits-all. There are several recognized subtypes, each with distinct patterns of mood episodes:

Bipolar I Disorder

Defined by at least one full manic episode lasting 7 or more days, sometimes requiring hospitalization. Depressive episodes frequently occur and can be severe.

Bipolar II Disorder

Characterized by recurrent major depressive episodes and hypomanic episodes (a milder form of mania). Often misdiagnosed as depression alone.

Cyclothymic Disorder

A milder, chronic form with numerous periods of hypomanic and depressive symptoms over two or more years, without meeting full criteria for either type.

Rapid Cycling

Four or more distinct mood episodes per year, occurring in Bipolar I or II. Often requires a carefully tailored, specialized treatment approach.

Treatment Approaches

Bipolar disorder is highly treatable. With the right combination of approaches, most people achieve significant mood stability and lead full, productive lives. Dr. Brendel tailors treatment to each patient’s specific subtype, episode history, and life circumstances:

Mood-Stabilizing Medications

Lithium, valproate, lamotrigine, and atypical antipsychotics are evidence-based medications that reduce the frequency and severity of mood episodes.

Psychotherapy & Psychoeducation

Cognitive behavioral therapy, interpersonal therapy, and psychoeducation help patients recognize triggers, build coping strategies, and maintain stability between episodes.

Lifestyle & Sleep Regulation

Consistent sleep schedules, stress reduction, and avoiding alcohol and substances are critical — lifestyle disruptions are among the most common triggers for mood episodes.

Long-term Integrated Care

Bipolar is a lifelong condition that benefits from a sustained treatment relationship. Dr. Brendel provides ongoing, adaptive care as each patient’s needs and life circumstances evolve over time.

I have treated patients with all types of bipolar disorder for over two decades. If you or a loved one may be experiencing symptoms, please contact me to discuss evaluation and treatment options. You can book an appointment online via ZocDoc, call (617) 932-1548, or email David@DrDavidBrendel.com.

Frequently Asked Questions


How is bipolar disorder diagnosed?

Bipolar disorder is diagnosed through a comprehensive psychiatric evaluation covering mood history, symptoms, family history, and medical background. There is no single blood test or brain scan. Accurate diagnosis — and distinguishing bipolar from depression, ADHD, and other conditions — requires an experienced clinician.

What is the difference between Bipolar I and Bipolar II?

Bipolar I is defined by full manic episodes that can be severe and sometimes require hospitalization. Bipolar II involves hypomanic episodes (less intense than full mania) alternating with major depressive episodes. Bipolar II is often misdiagnosed as unipolar depression because the hypomanic episodes can be subtle.

Can bipolar disorder be treated without medication?

While lifestyle changes and therapy are important, most people with bipolar disorder benefit significantly from mood-stabilizing medications. Medication helps prevent episode cycling that is difficult to control through lifestyle changes alone. Dr. Brendel works with each patient to find the right combination of treatments.

How long does treatment for bipolar disorder take?

Bipolar disorder is generally a long-term condition. Many patients require ongoing treatment to maintain mood stability and prevent relapse. Some achieve long periods of stability with the right plan; others need more active management. Dr. Brendel focuses on sustainable, long-term care tailored to each patient’s evolving needs.

Is bipolar disorder hereditary?

Bipolar disorder has a strong genetic component — having a first-degree relative with the condition significantly increases risk. However, genetics are not destiny; environmental factors, stress, and lifestyle also play important roles. A thorough family history is always part of Dr. Brendel’s evaluation.

What should I expect at my first appointment?

Your first visit is a comprehensive psychiatric evaluation, typically 60–90 minutes. Dr. Brendel will review your current symptoms, mood history, medical background, and any prior treatments — to gain a thorough understanding of your situation before recommending a personalized treatment plan.

Why Choose Dr. Brendel for Bipolar Disorder Treatment?


Dr. David Brendel brings over two decades of specialized experience evaluating and treating all types of bipolar disorder in the Greater Boston area. Here is what distinguishes his practice:

  • 25+ years treating bipolar disorder — extensive experience with Bipolar I, II, cyclothymia, and rapid cycling
  • Harvard-trained with an MD and PhD; board-certified by the American Board of Psychiatry and Neurology
  • Expert medication management: deep expertise with lithium, mood stabilizers, atypical antipsychotics, and lamotrigine
  • Precise diagnostic assessment: careful evaluation to distinguish bipolar from depression, ADHD, and other conditions that can mimic its symptoms
  • Integrated treatment approach: combines pharmacotherapy with psychotherapy, psychoeducation, and lifestyle optimization
  • Author of Healing Psychiatry (MIT Press) — rigorous academic background applied to personalized clinical care
  • Located in Belmont, MA, conveniently serving Greater Boston, Cambridge, and surrounding communities
  • Accepting new patientsbook online via ZocDoc or call (617) 932-1548

Bipolar disorder remains one of the most frequently misdiagnosed psychiatric conditions. Many patients spend years receiving treatment for unipolar depression before an accurate diagnosis is made — missing out on the mood stabilizers and tailored care that can make a transformative difference.

Dr. Brendel’s approach begins with a meticulous diagnostic evaluation and a thorough review of treatment history. He places particular emphasis on understanding each patient’s unique pattern of mood cycling, triggers, and response to prior medications — because what works for one patient may not work for another.

Whether you are newly diagnosed, seeking a second opinion, or struggling to achieve stability despite prior treatment, Dr. Brendel has the expertise and commitment to help you find a path forward.

Ready to Address Your Bipolar Disorder?

Dr. Brendel is currently accepting new patients for evaluation and treatment of bipolar disorder — personalized, evidence-based care tailored to your unique needs.

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